Formation and function of the immunological synapse.
Less than five years ago it was reported that cell surface molecules at the contact site between CD4 T cells and antigen-presenting cells redistribute into distinct patterns, forming an organized interface termed the immunological synapse. More recently, similar reorganized interfaces have been obse...
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| Format: | Journal article |
| Jezik: | English |
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2002
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| _version_ | 1826269659408629760 |
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| author | Van Der Merwe, P |
| author_facet | Van Der Merwe, P |
| author_sort | Van Der Merwe, P |
| collection | OXFORD |
| description | Less than five years ago it was reported that cell surface molecules at the contact site between CD4 T cells and antigen-presenting cells redistribute into distinct patterns, forming an organized interface termed the immunological synapse. More recently, similar reorganized interfaces have been observed with CD8 T cells and NK cells, suggesting that they may be a common feature of lymphocyte activation. Although there has been some advance in our understanding of the mechanisms underlying this redistribution, its purpose remains unclear and controversial. |
| first_indexed | 2024-03-06T21:28:33Z |
| format | Journal article |
| id | oxford-uuid:43e7218f-931c-454b-b845-ec94cf97c3db |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:28:33Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | oxford-uuid:43e7218f-931c-454b-b845-ec94cf97c3db2022-03-26T14:58:23ZFormation and function of the immunological synapse.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:43e7218f-931c-454b-b845-ec94cf97c3dbEnglishSymplectic Elements at Oxford2002Van Der Merwe, PLess than five years ago it was reported that cell surface molecules at the contact site between CD4 T cells and antigen-presenting cells redistribute into distinct patterns, forming an organized interface termed the immunological synapse. More recently, similar reorganized interfaces have been observed with CD8 T cells and NK cells, suggesting that they may be a common feature of lymphocyte activation. Although there has been some advance in our understanding of the mechanisms underlying this redistribution, its purpose remains unclear and controversial. |
| spellingShingle | Van Der Merwe, P Formation and function of the immunological synapse. |
| title | Formation and function of the immunological synapse. |
| title_full | Formation and function of the immunological synapse. |
| title_fullStr | Formation and function of the immunological synapse. |
| title_full_unstemmed | Formation and function of the immunological synapse. |
| title_short | Formation and function of the immunological synapse. |
| title_sort | formation and function of the immunological synapse |
| work_keys_str_mv | AT vandermerwep formationandfunctionoftheimmunologicalsynapse |