Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance

Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance

<p><strong>OBJECTIVE:</strong> Dysregulated immune responses are the cause of IBDs. Studies in mice and humans suggest a central role of interleukin (IL)-23-producing mononuclear phagocytes in disease pathogenesis. Mechanistic insights into the regulation of IL-23 are prerequisite...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Aschenbrenner, D, Quaranta, M, Banerjee, S, Ilott, N, Jansen, J, Steere, B, Chen, Y-H, Ho, S, Cox, K, Arancibia-Cárcamo, CV, Coles, M, Gaffney, E, Travis, SP, Denson, L, Kugathasan, S, Schmitz, J, Powrie, F, Sansom, SN, Uhlig, HH
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: BMJ 2020

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