DIRECT OBSERVATION OF A TETRAHEDRAL BORONIC ACID BETA-LACTAMASE COMPLEX USING B-11 NMR-SPECTROSCOPY
A tetrahedral boronic acid-β-lactamase complex formed by treatment of the P99 β-lactamase enzyme from Enterobacter cloacae with 3-dansylamidophenylboronic acid has been directly observed using 11B NMR spectroscopy.
Main Authors: | Baldwin, J, Claridge, T, Derome, A, Smith, B, Twyman, M, Waley, S |
---|---|
Format: | Journal article |
Udgivet: |
1991
|
Lignende værker
-
B-11 NMR-STUDIES OF AN ARYL BORONIC ACID BOUND TO CHYMOTRYPSIN AND SUBTILISIN
af: Baldwin, J, et al.
Udgivet: (1991) -
Use of electrospray mass spectrometry to directly observe an acyl enzyme intermediate in beta-lactamase catalysis.
af: Aplin, RT, et al.
Udgivet: (1990) -
Site-directed mutagenesis of beta-lactamase I: role of Glu-166.
af: Leung, Y, et al.
Udgivet: (1994) -
EQUIPMENT FOR SELECTIVE EXCITATION IN NMR-SPECTROSCOPY - ENHANCED TECHNIQUES FOR RADIOFREQUENCY MODULATION AND DIGITAL PULSE-SHAPE GENERATION
af: Gregory, N, et al.
Udgivet: (1994) -
Monitoring conformational changes in the NDM-1 metallo-β-lactamase by 19F NMR spectroscopy.
af: Rydzik, A, et al.
Udgivet: (2014)