Local field potential beta activity in the subthalamic nucleus of patients with Parkinson's disease is associated with improvements in bradykinesia after dopamine and deep brain stimulation.
Parkinson's disease is treated pharmacologically with dopamine replacement medication and, more recently, by stimulating basal-ganglia nuclei such as the subthalamic nucleus (STN). Depth recordings after this procedure have revealed excessive activity at frequencies between 8 and 35 Hz (Brown e...
Main Authors: | Ray, N, Jenkinson, N, Wang, S, Holland, P, Brittain, J, Joint, C, Stein, J, Aziz, T |
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Format: | Journal article |
Language: | English |
Published: |
2008
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