The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system.
The dopamine receptor antagonist fluphenazine decanoate, when administered for a total period of 10 months, produced a large increase in neurotensin-like immunoreactivity in dopamine-rich brain areas, such as the nucleus accumbens, the striatum and the frontal cortex. A smaller, non-significant incr...
| Main Authors: | , , |
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| פורמט: | Journal article |
| שפה: | English |
| יצא לאור: |
1985
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| _version_ | 1826269688791826432 |
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| author | Goedert, M Iversen, S Emson, P |
| author_facet | Goedert, M Iversen, S Emson, P |
| author_sort | Goedert, M |
| collection | OXFORD |
| description | The dopamine receptor antagonist fluphenazine decanoate, when administered for a total period of 10 months, produced a large increase in neurotensin-like immunoreactivity in dopamine-rich brain areas, such as the nucleus accumbens, the striatum and the frontal cortex. A smaller, non-significant increase was observed in the substantia nigra with no change in either the hypothalamus or the spinal cord. The present results provide further evidence in favour of a functional interaction between neurotensin and dopamine in the central nervous system. |
| first_indexed | 2024-03-06T21:29:01Z |
| format | Journal article |
| id | oxford-uuid:44073c73-6d30-4bca-a4d3-103a9edcfc2b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:29:01Z |
| publishDate | 1985 |
| record_format | dspace |
| spelling | oxford-uuid:44073c73-6d30-4bca-a4d3-103a9edcfc2b2022-03-26T14:59:15ZThe effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:44073c73-6d30-4bca-a4d3-103a9edcfc2bEnglishSymplectic Elements at Oxford1985Goedert, MIversen, SEmson, PThe dopamine receptor antagonist fluphenazine decanoate, when administered for a total period of 10 months, produced a large increase in neurotensin-like immunoreactivity in dopamine-rich brain areas, such as the nucleus accumbens, the striatum and the frontal cortex. A smaller, non-significant increase was observed in the substantia nigra with no change in either the hypothalamus or the spinal cord. The present results provide further evidence in favour of a functional interaction between neurotensin and dopamine in the central nervous system. |
| spellingShingle | Goedert, M Iversen, S Emson, P The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system. |
| title | The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system. |
| title_full | The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system. |
| title_fullStr | The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system. |
| title_full_unstemmed | The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system. |
| title_short | The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system. |
| title_sort | effects of chronic neuroleptic treatment on neurotensin like immunoreactivity in the rat central nervous system |
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