A novel rat model of liver regeneration: possible role of cytokine induced neutrophil chemoattractant-1 in augmented liver regeneration
Liver resection is the mainstay of treatment for most of the liver tumors. Liver has a unique capability to restore the lost volume following resection, however, most of the primary tumors grow in a liver with preexisting parenchymal diseases and secondary tumors often present in multiple liver lobe...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Published: |
BioMed Central
2015
|
| _version_ | 1797065515241308160 |
|---|---|
| author | Dhar, D Mohammad, G Vyas, S Broering, D Malago, M |
| author_facet | Dhar, D Mohammad, G Vyas, S Broering, D Malago, M |
| author_sort | Dhar, D |
| collection | OXFORD |
| description | Liver resection is the mainstay of treatment for most of the liver tumors. Liver has a unique capability to restore the lost volume following resection, however, most of the primary tumors grow in a liver with preexisting parenchymal diseases and secondary tumors often present in multiple liver lobes precluding a safe curative resection. Two-stage hepatectomy and portal vein ligation (PVL) are used to achieve a safer future remnant liver volume (FRLV), however, these procedures take several weeks to achieve adequate FRLV. A recently introduced faster alternative two-stage hepatectomy, also know as associated liver partitioning and portal vein ligation for staged hepatectomy (ALPPS), produces a desirable FRLV in days. |
| first_indexed | 2024-03-06T21:29:42Z |
| format | Journal article |
| id | oxford-uuid:444330ee-1d8c-46ab-ba09-1059ee23d7dd |
| institution | University of Oxford |
| last_indexed | 2024-03-06T21:29:42Z |
| publishDate | 2015 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:444330ee-1d8c-46ab-ba09-1059ee23d7dd2022-03-26T15:00:33ZA novel rat model of liver regeneration: possible role of cytokine induced neutrophil chemoattractant-1 in augmented liver regenerationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:444330ee-1d8c-46ab-ba09-1059ee23d7ddSymplectic Elements at OxfordBioMed Central2015Dhar, DMohammad, GVyas, SBroering, DMalago, MLiver resection is the mainstay of treatment for most of the liver tumors. Liver has a unique capability to restore the lost volume following resection, however, most of the primary tumors grow in a liver with preexisting parenchymal diseases and secondary tumors often present in multiple liver lobes precluding a safe curative resection. Two-stage hepatectomy and portal vein ligation (PVL) are used to achieve a safer future remnant liver volume (FRLV), however, these procedures take several weeks to achieve adequate FRLV. A recently introduced faster alternative two-stage hepatectomy, also know as associated liver partitioning and portal vein ligation for staged hepatectomy (ALPPS), produces a desirable FRLV in days. |
| spellingShingle | Dhar, D Mohammad, G Vyas, S Broering, D Malago, M A novel rat model of liver regeneration: possible role of cytokine induced neutrophil chemoattractant-1 in augmented liver regeneration |
| title | A novel rat model of liver regeneration: possible role of cytokine induced neutrophil chemoattractant-1 in augmented liver regeneration |
| title_full | A novel rat model of liver regeneration: possible role of cytokine induced neutrophil chemoattractant-1 in augmented liver regeneration |
| title_fullStr | A novel rat model of liver regeneration: possible role of cytokine induced neutrophil chemoattractant-1 in augmented liver regeneration |
| title_full_unstemmed | A novel rat model of liver regeneration: possible role of cytokine induced neutrophil chemoattractant-1 in augmented liver regeneration |
| title_short | A novel rat model of liver regeneration: possible role of cytokine induced neutrophil chemoattractant-1 in augmented liver regeneration |
| title_sort | novel rat model of liver regeneration possible role of cytokine induced neutrophil chemoattractant 1 in augmented liver regeneration |
| work_keys_str_mv | AT dhard anovelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT mohammadg anovelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT vyass anovelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT broeringd anovelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT malagom anovelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT dhard novelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT mohammadg novelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT vyass novelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT broeringd novelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration AT malagom novelratmodelofliverregenerationpossibleroleofcytokineinducedneutrophilchemoattractant1inaugmentedliverregeneration |