Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

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Glucose-6-phosphate dehydrogenase (G6PD) deficiency is believed to confer protection against Plasmodium falciparum malaria, but the precise nature of the protective effecthas proved difficult to define as G6PD deficiency has multiple allelic variants with different effects in males and females, and...

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Bibliographic Details
Main Authors: Clarke, G, Rockett, K, Kivinen, K, Hubbart, C, Jeffreys, A, Rowlands, K, Jallow, M, Conway, D, Bojang, K, Pinder, M, Usen, S, Sisay-Joof, F, Sirugo, G, Toure, O, Thera, M, Konate, S, Sissoko, S, Niangaly, A, Poudiougou, B, Mangano, V, Bougouma, E, Sirima, S, Modiano, D, Amenga-Etego, L, Ghansah, A, Koram, K, Wilson, M, Enimil, A, Evans, J, Amodu, O, Olaniyan, S, Apinjoh, T, Mugri, R, Ndi, A, Ndila, C, Uyoga, S, Macharia, A, Peshu, N, Williams, T, Manjurano, A, Sepúlveda, N, Clark, T, Riley, E, Drakeley, C, Reyburn, H, Nyirongo, V, Kachala, D, Molyneux, M, Dunstan, S, Phu, N, Quyen, N, Thai, C, Hien, T, Manning, L, Laman, M, Siba, P, Karunajeewa, H, Allen, S, Allen, A, Davis, T, Michon, P, Mueller, I, Molloy, S, Campino, S, Kerasidou, A, Cornelius, V, Hart, L, Shah, S, Band, G, Spencer, C, Agbenyega, T, Achidi, E, Doumbo, O, Farrar, J, Marsh, K, Taylor, T, Kwiatkowski, D, MalariaGEN Consortium
Format: Journal article
Language:English
Published: eLife Sciences Publications 2017

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