In vivo functions mediated by the p41 isoform of the MHC class II-associated invariant chain.
We used a "hit and run" gene targeting strategy to generate mice expressing only the p41 isoform of the conserved invariant (Ii) chain associated with MHC class II molecules. In contrast to mutants expressing only p31 Ii chain, a small proportion of A(alpha)b A(beta)b molecules produced by...
Main Authors: | Takaesu, N, Lower, J, Yelon, D, Robertson, E, Bikoff, E |
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Format: | Journal article |
Language: | English |
Published: |
1997
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