Transfection of thyroid autoantigens into EBV-transformed B cell lines. Recognition by Graves' disease thyroid T cells.

Transfection of thyroid autoantigens into EBV-transformed B cell lines. Recognition by Graves' disease thyroid T cells.

Autologous EBV-transformed B cell lines (EBVL) from a patient with Graves' disease (GD) were transfected with the expression vector pREP4 encoding thyroid peroxidase (TPO), the thyroid-stimulating hormone receptor (TSHR), or chloramphenicol acetyl transferase. The relevant proteins were express...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Mullins, R, Chernajovsky, Y, Dayan, C, Londei, M, Feldmann, M
Natura:	Journal article
Lingua:	English
Pubblicazione:	1994

Documenti analoghi

Identification of thyroid stimulating hormone receptor-specific T cells in Graves' disease thyroid using autoantigen-transfected Epstein-Barr virus-transformed B cell lines.
di: Mullins, R, et al.
Pubblicazione: (1995)

Autoantigen recognition by thyroid-infiltrating T cells in Graves disease.
di: Dayan, C, et al.
Pubblicazione: (1991)

Mechanism of Graves thyroiditis: implications for concepts and therapy of autoimmunity.
di: Feldmann, M, et al.
Pubblicazione: (1992)

Human T-cell clones from autoimmune thyroid glands: specific recognition of autologous thyroid cells.
di: Londei, M, et al.
Pubblicazione: (1985)

T cell activation and antigen presentation in human thyroid autoimmunity.
di: Feldmann, M, et al.
Pubblicazione: (1992)

Autoimmune thyroiditis and targeted anti-T cell immunotherapy in man.
di: Dayan, C, et al.
Pubblicazione: (1992)

Analysis of T-cell receptor usage in activated T-cell clones from Hashimoto's thyroiditis and Graves' disease.
di: Lipoldova, M, et al.
Pubblicazione: (1989)

Pathogenetic relevance of HLA class II expressing thyroid follicular cells in nontoxic Goiter and in Graves' disease.
di: Grubeck-Loebenstein, B, et al.
Pubblicazione: (1988)

AUTOANTIGEN PRESENTATION BY TARGET-CELLS - ITS POSSIBLE ROLE IN DETERMINING AUTOANTIBODY SPECIFICITY
di: Todd, I, et al.
Pubblicazione: (1986)

B‐cell receptors of EBV‐negative Burkitt lymphoma bind modified isoforms of autoantigens
di: Theresa Bock, et al.
Pubblicazione: (2022-08-01)

Inappropriate major histocompatibility complex class II expression by thyroid follicular cells in thyroid autoimmune disease and by pancreatic beta cells in type I diabetes.
di: Pujol-Borrell, R, et al.
Pubblicazione: (1986)

Expression of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-3 on human thyroid epithelial cells in Graves' and Hashimoto's diseases.
di: Zheng, R, et al.
Pubblicazione: (1990)

Comparison of the cellular infiltrate of Hashimoto's thyroiditis in vivo and after in vitro cell growth.
di: Londei, M, et al.
Pubblicazione: (1987)

Modelling of Thyroid Peroxidase Reveals Insights into Its Enzyme Function and Autoantigenicity.
di: Sarah N Le, et al.
Pubblicazione: (2015-01-01)

New ideas in thyroid autoimmunity.
di: Pujol-Borrell, R, et al.
Pubblicazione: (1987)

Intrathyroidal cytokine production in thyroid disease.
di: Grubeck-Loebenstein, B, et al.
Pubblicazione: (1989)

Analysis of intrathyroidal cytokine production in thyroid autoimmune disease: thyroid follicular cells produce interleukin-1 alpha and interleukin-6.
di: Grubeck-Loebenstein, B, et al.
Pubblicazione: (1989)

Characterization of Regulatory B Cells in Graves' Disease and Hashimoto's Thyroiditis.
di: Birte Kristensen, et al.
Pubblicazione: (2015-01-01)

The role of Graves’ disease in the development of thyroid nodules and thyroid cancer
di: Marta Nascimento Soares, et al.
Pubblicazione: (2023-07-01)

Autoimmune Thyroiditis Shifting from Hashimoto’s Thyroiditis to Graves’ Disease
di: Narantsatsral Daramjav, et al.
Pubblicazione: (2023-04-01)

Thyroid Ultrasonography in Differentiation between Graves’ Disease and Hashimoto’s Thyroiditis
di: Pishdad P., et al.
Pubblicazione: (2017-03-01)

Thyroid ima artery embolization for the treatment of Graves’ disease and thyroid storm
di: Maximilian Bonnici, ScM, et al.
Pubblicazione: (2023-08-01)

Graves' disease diagnosed in remnant thyroid after lobectomy for thyroid cancer.
di: Meihua Jin, et al.
Pubblicazione: (2022-01-01)

Frequency of thyroid nodules and thyroid cancer in thyroidectomized patients with Graves’ disease
di: Caglar Keskin, et al.
Pubblicazione: (2019-01-01)

CD4+ T-cell clones from autoimmune thyroid tissue cannot be classified according to their lymphokine production.
di: Grubeck-Loebenstein, B, et al.
Pubblicazione: (1990)

Graves’ ophthalmopathy – thyroid eye disease
di: Dagna Siedlecka, et al.
Pubblicazione: (2019-08-01)

T Cell Recognition of Autoantigens in Human Type 1 Diabetes: Clinical Perspectives
di: Roberto Mallone, et al.
Pubblicazione: (2011-01-01)

Reactivity to Novel Autoantigens in Patients with Coexisting Central Nervous System Demyelinating Disease and Autoimmune Thyroid Disease
di: Judith M. Greer, et al.
Pubblicazione: (2017-05-01)

Amino acid sequence homology between thyroid autoantigens and central nervous system proteins: Implications for the steroid-responsive encephalopathy associated with autoimmune thyroiditis
di: Salvatore Benvenga, et al.
Pubblicazione: (2021-12-01)

Thyroid cancer cell lines: an overview
di: Manuel eSaiselet, et al.
Pubblicazione: (2012-11-01)

Targeted immunotherapies for Graves’ thyroidal & orbital diseases
di: Alan Chun Hong Lee, et al.
Pubblicazione: (2025-03-01)

Graves’ disease, myxedema and papillary thyroid carcinoma
di: Luiz Augusto Marin Jaca, et al.
Pubblicazione: (2022-12-01)

Thyroid hormone resistance misdiagnosed as Graves' disease
di: Manish Gutch, et al.
Pubblicazione: (2017-01-01)

Riedel Thyroiditis in a Patient with Graves Disease
di: Doo Young Lee, et al.
Pubblicazione: (2013-06-01)

Anti-thyroid drugs in pediatric Graves′ disease
di: Mathew John, et al.
Pubblicazione: (2015-01-01)

Vascular Cell Adhesion Molecule-l (VCAM-l) in Graves' Disease: Its Association to Thyroid Status and Thyroid Receptor Stimulating Antibodies
di: Wan Nazaimoon, W.M., et al.
Pubblicazione: (2004)

Clinical course of thyroid function and thyroid associated-ophthalmopathy in patients with euthyroid Graves’ disease
di: Suzuki N, et al.
Pubblicazione: (2018-04-01)

Factors Governing B Cell Recognition of Autoantigen and Function in Type 1 Diabetes
di: Lindsay E. Bass, et al.
Pubblicazione: (2024-04-01)

Incidence of the postpartum diagnosis of thyroid eye disease in relation to thyroid function in Graves’ disease
di: Nami Suzuki, et al.
Pubblicazione: (2025-01-01)

Prevalence of Papillary Thyroid Carcinoma is Significantly Higher in Graves Disease with Synchronous Thyroid Nodules
di: Mehmet KEFELI, et al.
Pubblicazione: (2024-09-01)