Transfection of thyroid autoantigens into EBV-transformed B cell lines. Recognition by Graves' disease thyroid T cells.
Autologous EBV-transformed B cell lines (EBVL) from a patient with Graves' disease (GD) were transfected with the expression vector pREP4 encoding thyroid peroxidase (TPO), the thyroid-stimulating hormone receptor (TSHR), or chloramphenicol acetyl transferase. The relevant proteins were express...
Váldodahkkit: | Mullins, R, Chernajovsky, Y, Dayan, C, Londei, M, Feldmann, M |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
1994
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Geahča maid
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Identification of thyroid stimulating hormone receptor-specific T cells in Graves' disease thyroid using autoantigen-transfected Epstein-Barr virus-transformed B cell lines.
Dahkki: Mullins, R, et al.
Almmustuhtton: (1995) -
Autoantigen recognition by thyroid-infiltrating T cells in Graves disease.
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Almmustuhtton: (1991) -
Mechanism of Graves thyroiditis: implications for concepts and therapy of autoimmunity.
Dahkki: Feldmann, M, et al.
Almmustuhtton: (1992) -
Human T-cell clones from autoimmune thyroid glands: specific recognition of autologous thyroid cells.
Dahkki: Londei, M, et al.
Almmustuhtton: (1985) -
T cell activation and antigen presentation in human thyroid autoimmunity.
Dahkki: Feldmann, M, et al.
Almmustuhtton: (1992)