Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.
The rates of escape and reversion in response to selection pressure arising from the host immune system, notably the cytotoxic T-lymphocyte (CTL) response, are key factors determining the evolution of HIV. Existing methods for estimating these parameters from cross-sectional population data using or...
| Main Authors: | , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
2013
|