Doubly diastereoselective conjugate additions of the antipodes of lithium N-benzyl-N-(alpha-methylbenzyl)amide to enantiopure epsilon-O-protected alpha,beta-unsaturated esters derived from D-ribose
Enantiopure ε-O-silyloxy- and ε-O-benzyloxy-α,β-unsaturated esters derived from d-ribose, each containing a cis-dioxolane unit, display excellent (≥95:5 dr) levels of diastereofacial directing ability upon conjugate addition of achiral lithium N-benzyl-N-isopropylamide. In contrast to the correspond...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Published: |
2014
|