Structural characterisation of the interaction between Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) and their human ligands in severe malaria
<p>Sequestration of infected erythrocytes during P. falciparum infection can lead to severe malaria. PfEMP1 proteins are central to this process. Multimodular PfEMP1 proteins can bind to a variety of human ligands due to the presence of CIDR and DBL domains. CIDR and DBL domains are classified...
Main Author: | Ng, HK |
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Other Authors: | Higgins, M |
Format: | Thesis |
Language: | English |
Published: |
2012
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Subjects: |
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