The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core
Redox regulated effector systems that counteract oxidative stress are essential for all forms of life. Here, we uncover a new paradigm for sensing oxidative stress centred on the hydrophobic core of a sensor protein. RsrA is an archetypal zinc-binding anti-sigma factor that responds to disulfide s...
Main Authors: | Rajasekar, K, Zdanowski, K, Yan, J, Hopper, J, Francis, M, Seepersad, C, Sharp, C, Pecqueur, L, Werner, J, Robinson, C, Mohammed, S, Potts, J, Kleanthous, C |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group: Nature Communications
2016
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