The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core

The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core

Redox regulated effector systems that counteract oxidative stress are essential for all forms of life. Here, we uncover a new paradigm for sensing oxidative stress centred on the hydrophobic core of a sensor protein. RsrA is an archetypal zinc-binding anti-sigma factor that responds to disulfide s...

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Bibliografiska uppgifter
Huvudupphovsmän: Rajasekar, K, Zdanowski, K, Yan, J, Hopper, J, Francis, M, Seepersad, C, Sharp, C, Pecqueur, L, Werner, J, Robinson, C, Mohammed, S, Potts, J, Kleanthous, C
Materialtyp: Journal article
Språk:English
Publicerad: Nature Publishing Group: Nature Communications 2016

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