Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells

Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells

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Objective: To examine the underlying factors leading to infertility in a male patient from whom phospholipase C zeta H398P (PLCζ H398P, histidine > proline) and PLCζ H233L (histidine > leucine) mutations were previously identified. Desi...

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Detalhes bibliográficos
Main Authors:	Kashir, J, Konstantinidis, M, Jones, C, Heindryckx, B, De Sutter, P, Parrington, J, Wells, D, Coward, K
Formato:	Journal article
Idioma:	English
Publicado em:	2012

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