Investigation of osteoclastogenic signalling of the RANKL substitute LIGHT.

Investigation of osteoclastogenic signalling of the RANKL substitute LIGHT.

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LIGHT (TNFSF14) is a member of the TNF superfamily and is known to substitute for RANKL to induce osteoclast differentiation. LIGHT binds HVEM and LTβR, but it is not known whether these receptors play a role in osteoclast formation or whether LIGHT acts via RANKL signalling pathways. We found that...

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Autors principals:	Hemingway, F, Kashima, T, Knowles, H, Athanasou, N
Format:	Journal article
Idioma:	English
Publicat:	2013

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