Investigation of osteoclastogenic signalling of the RANKL substitute LIGHT.

LIGHT (TNFSF14) is a member of the TNF superfamily and is known to substitute for RANKL to induce osteoclast differentiation. LIGHT binds HVEM and LTβR, but it is not known whether these receptors play a role in osteoclast formation or whether LIGHT acts via RANKL signalling pathways. We found that...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Hemingway, F, Kashima, T, Knowles, H, Athanasou, N
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2013