Efficient protein production inspired by how spiders make silk.

Efficient protein production inspired by how spiders make silk.

Membrane proteins are targets of most available pharmaceuticals, but they are difficult to produce recombinantly, like many other aggregation-prone proteins. Spiders can produce silk proteins at huge concentrations by sequestering their aggregation-prone regions in micellar structures, where the ver...

Bibliografski detalji
Glavni autori:	Kronqvist, N, Sarr, M, Lindqvist, A, Nordling, K, Otikovs, M, Venturi, L, Pioselli, B, Purhonen, P, Landreh, M, Biverstål, H, Toleikis, Z, Sjöberg, L, Robinson, C, Pelizzi, N, Jörnvall, H, Hebert, H, Jaudzems, K, Curstedt, T, Rising, A, Johansson, J
Format:	Journal article
Jezik:	English
Izdano:	Nature Publishing Group 2017

Slični predmeti

Efficient protein production inspired by how spiders make silk
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od: PORAV Viorica
Izdano: (2014-05-01)

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od: Gabriele Greco, i dr.
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od: M. Haghighatkish, i dr.
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Izdano: (2006)

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od: Benjamin Schmuck, i dr.
Izdano: (2022-11-01)

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od: Anna eRising, i dr.
Izdano: (2014-11-01)

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od: Hakimi, O, i dr.
Izdano: (2006)

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od: Kojić, Nikola, 1978-
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od: H. M. Tahir, i dr.
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Deformation micromechanics of spider silk
od: Brookes, V, i dr.
Izdano: (2008)

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od: Simon Fruergaard, i dr.
Izdano: (2021-10-01)

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od: Robin Meadows
Izdano: (2014-08-01)

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od: Gabriele Greco, i dr.
Izdano: (2020-07-01)

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od: Kucharczyk K, i dr.
Izdano: (2018-07-01)

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od: Monk, J, i dr.
Izdano: (2016)

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Izdano: (2024-01-01)

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Izdano: (2023-09-01)

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od: Vollrath, F, i dr.
Izdano: (2006)

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Izdano: (2012-01-01)

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od: Brown, C, i dr.
Izdano: (2011)

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od: Porter, D, i dr.
Izdano: (2013)

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od: Hakimi, O, i dr.
Izdano: (2007)

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Izdano: (2021-03-01)

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Izdano: (2022-08-01)

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