Efficient protein production inspired by how spiders make silk.
Membrane proteins are targets of most available pharmaceuticals, but they are difficult to produce recombinantly, like many other aggregation-prone proteins. Spiders can produce silk proteins at huge concentrations by sequestering their aggregation-prone regions in micellar structures, where the ver...
Huvudupphovsmän: | , , , , , , , , , , , , , , , , , , , |
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Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
Nature Publishing Group
2017
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