Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates

Regulatory T cells (Tregs) play an important role in controlling inflammation and limiting autoimmunity, but their phenotypes at inflammatory sites in human disease are poorly understood. We here analyze the single-cell transcriptome of >16,000 Tregs obtained from peripheral blood and synovial fl...

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Hlavní autoři: Simone, D, Penkava, F, Ridley, A, Sansom, S, Al-Mossawi, M, Bowness, P
Médium: Journal article
Jazyk:English
Vydáno: Springer Nature 2021