Haematopoietic stem/progenitor cell interactions with the bone marrow vascular niche

Umbilical cord blood (UCB) is used as a source of haematopoietic stem cells (HSCs) for transplantation but shows defective homing to the bone marrow niche and delayed haematological reconstitution. Following transplantation, HSCs will home to the bone marrow in response to the CXCL12 chemokine, adhe...

Full description

Bibliographic Details
Main Author: Chang, CH
Other Authors: Watt, S
Format: Thesis
Language:English
Published: 2013
Subjects: