Competing discrete interfacial effects are critical for amyloidogenesis.

Amyloid accumulation is associated with pathological conditions, including type II diabetes and Alzheimer's disease. Lipids influence amyloidogenesis and are themselves targets for amyloid-mediated cell membrane disruption. Amyloid precursors are surface-active, accumulating at hydrophobic-hydr...

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Bibliographic Details
Main Authors: Jean, L, Lee, C, Shaw, M, Vaux, D
Format: Journal article
Language:English
Published: 2010