Chemical and biological studies on human oxygenases

Chemical and biological studies on human oxygenases

<p>As depicted in Chapter I, 2-oxoglutarate- (2OG) dependent oxygenases are ubiquitous in living systems and display a wide range of cellular functions, spanning metabolism, transcription, and translation. Although functionally diverse, the 2OG oxygenases share a high degree of structural simi...

Bibliografski detalji
Glavni autori:	Thinnes, C, Dr Cyrille C. Thinnes
Daljnji autori:	Schofield, C
Format:	Disertacija
Jezik:	English
Izdano:	2014
Teme:	Chemical biology Chemistry & allied sciences Business Entrepreneurship Structural genomics Oncology Biophysical chemistry Science and technology (business & management) Marketing Physical Sciences Pharmacology Cell Biology (see also Plant sciences) Management Biochemistry Enzymes Life Sciences Genetics (life sciences) Polymers Amino acid and peptide chemistry Organic synthesis Synthetic organic chemistry Organic chemistry Business and Management Protein chemistry Chemical kinetics Computer aided molecular and material design Biology

Slični predmeti

NMR studies on 2-oxoglutarate oxygenases
od: Leung, IKH
Izdano: (2013)

Development of small molecule inhibitors of the bromodomain-histone interaction
od: Rooney, TPC
Izdano: (2014)

Olefin metathesis for site-selective protein modification
od: Lin, YA
Izdano: (2013)

Design and synthesis of myo-inositol (1,4,5)-trisphosphate receptor antagonists
od: Ye, Y
Izdano: (2013)

A glycopore for bacterial sensing
od: Shanley, SJ
Izdano: (2009)

Single-molecule chemistry studies with engineered alpha-hemolysin pores
od: Hammerstein, A
Izdano: (2011)

Developing inhibitors of bromodomain-histone interactions
od: Hewings, D
Izdano: (2014)

Interplay between 2-oxoglutarate oxygenases and cancer: studies on the aspartyl/asparaginyl-beta-hydroxylase
od: Pfeffer, I
Izdano: (2014)

Peptide targeting by spontaneous isopeptide bond formation
od: Zakeri, B, i dr.
Izdano: (2011)

Kinetic and mechanistic studies of oxygen sensing Fe(II)/2-oxoglutarate dependent oxygenases
od: Tarhonskaya, H
Izdano: (2014)

Synthesis of Mycobacterium tuberculosis ATP synthase inhibitors
od: Pattarakiat, Seankongsuk
Izdano: (2022)

Studies on an N-terminal nucleophile hydrolase and enzymes of clavulanic acid biosynthesis
od: Iqbal, A
Izdano: (2008)

Mechanistic and inhibition studies on gamma-butyrobetaine hydroxylase
od: Rydzik, AM
Izdano: (2014)

Conformational control by intramolecular hydrogen bonding
od: Luccarelli, J, i dr.
Izdano: (2013)

Enzymatic and structural insights into the mycobacterial alkylhydroperoxide reductase subunit C and repurposing of an antimalaria compound inhibiting the mycobacterial cytochrome BCC oxidase for tuberculosis disease
od: Chong, Sherilyn Shi Min
Izdano: (2020)

Asymmetric syntheses of β- and γ-amino acids
od: Zammit, C
Izdano: (2015)

Aziridinations of tethered allenes
od: Feast, GC
Izdano: (2011)

Alkaloids from transannular iodoaminations
od: Brock, E
Izdano: (2012)

Versatile synthetic strategies towards the development of novel neuroblastoma inhibitors and their analogues
od: Alishahi, S
Izdano: (2013)

Studies towards the stereoselective synthesis of alkenes
od: Arif, T
Izdano: (2011)

Analysis of potassium (K+) efflux systems (Kef) as an antibiotic target in pathogenic bacteria
od: Haslam, C
Izdano: (2019)

Exploring and exploiting selectivity in Rhodium-catalysed hydroacylation reactions
od: Poingdestre, SJ
Izdano: (2012)

Radical cascades using enantioenriched 7-azabenzonorbornenes and their applications in synthesis
od: Hodgson, D, i dr.
Izdano: (2008)

Enantiorecognition phenomena in asymmetric synthesis
od: Yin, J, i dr.
Izdano: (2011)

Synthesis of 2,4,6-trisubstituted pyridines via an olefin cross-metathesis/Heck-cyclisation-elimination sequence.
od: Donohoe, T, i dr.
Izdano: (2011)

Reaction engineering for protein modification: tools for chemistry and biology
od: Chalker, J
Izdano: (2011)

Design and synthesis of inositol phosphate-based probes
od: Slowey, A
Izdano: (2013)

The synthesis of branched sugars and iminosugars
od: Parry, LL
Izdano: (2011)

Asymmetric synthesis of α-alkylated aldehydes using chiral enamines
od: Kaka, N, i dr.
Izdano: (2008)

Towards the total synthesis of calyciphylline A-type Daphniphyllum alkaloids
od: Michaelides, IN
Izdano: (2014)

Transition metal catalysed C-C bond formation via C-H functionalisation
od: Truscott, FR
Izdano: (2012)

Palladium mediated allylic fluorination
od: Hollingworth, C
Izdano: (2013)

Determining the structures of halogenated marine natural products by total synthesis
od: Dyson, BS
Izdano: (2011)

Tandem catalytic processes involving Rhodium-catalysed intermolecular hydroacylation
od: Lenden, P
Izdano: (2011)

Molecular dynamics simulation of the M2 helices within the nicotinic acetylcholine receptor transmembrane domain: structure and collective motions
Izdano: (2005)

Studies towards the total synthesis of manzamine A
od: Hawkins, A
Izdano: (2013)

Palladium-catalysed cascade cyclisation of alkynyl silanes and studies towards rubriflordilactone A
od: Cordonnier, M, i dr.
Izdano: (2011)

The synthesis and biology of iminosugars and their precursors
od: Ayers, B, i dr.
Izdano: (2014)

Discovery, characterization, and applications of cysteine-rich peptides from medicinal plants
od: Huang, Jiayi
Izdano: (2020)

Perylene-derived single-component organic nanoparticles with tunable emission : efficient anticancer drug carriers with real-time Monitoring of drug release
od: Li, Xin, i dr.
Izdano: (2014)