Acetaminophen as a renoprotective adjunctive treatment in patients with severe and moderately severe Falciparum malaria: a randomized, controlled, open-label trial

Acetaminophen as a renoprotective adjunctive treatment in patients with severe and moderately severe Falciparum malaria: a randomized, controlled, open-label trial

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Acute kidney injury independently predicts mortality in falciparum malaria. It is not known whether acetaminophen's capacity to inhibit plasma hemoglobin-mediated oxidation is renoprotective in severe malaria.A phase 2, open-label, randomized controlled trial at two hospitals in Bangladesh was...

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Hauptverfasser: Plewes, K, Kingston, HWF, Ghose, A, Wattanakul, T, Hassan, MMU, Haider, MS, Dutta, PK, Islam, MA, Alam, S, Jahangir, SM, Zahed, ASM, Sattar, MA, Chowdhury, MAH, Herdman, MT, Leopold, SJ, Ishioka, H, Piera, KA, Charunwatthana, P, Silamut, K, Yeo, TW, Lee, SJ, Mukaka, M, Maude, RJ, Turner, GDH, Faiz, MA, Tarning, J, Oates, JA, Anstey, NM, White, NJ, Day, NPJ, Hossain, MA, Roberts, LJ, Dondorp, AM
Format: Journal article
Sprache:English
Veröffentlicht: Oxford University Press 2018

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