Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection.

Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection.

The complement cascade defines an important link between the innate and the specific immune system. Here we show that mice deficient for the third component of complement (C3-/- mice) are highly susceptible to primary infection with influenza virus. C3-/- mice showed delayed viral clearance and incr...

Descripció completa

Dades bibliogràfiques
Autors principals:	Kopf, M, Abel, B, Gallimore, A, Carroll, M, Bachmann, M
Format:	Journal article
Idioma:	English
Publicat:	2002

Ítems similars

Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection.
per: Schmitz, N, et al.
Publicat: (2005)

Role of IgM antibodies versus B cells in influenza virus-specific immunity.
per: Kopf, M, et al.
Publicat: (2002)

Influenza virus: a novel method to assess viral and neutralizing antibody titers in vitro.
per: Bachmann, M, et al.
Publicat: (1999)

Complement-Independent Modulation of Influenza A Virus Infection by Factor H
per: Valarmathy Murugaiah, et al.
Publicat: (2020-03-01)

The role of B cells in acute and chronic infections.
per: Bachmann, M, et al.
Publicat: (1999)

Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection.
per: Kopf, M, et al.
Publicat: (2000)

The role of the priming loop in influenza A virus RNA synthesis
per: Te Velthuis, A, et al.
Publicat: (2016)

OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection.
per: Kopf, M, et al.
Publicat: (1999)

Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1.
per: Gatto, D, et al.
Publicat: (2005)

The Value of Targeting Complement Components in Asthma
per: Marwa M. E. Mohamed, et al.
Publicat: (2020-08-01)

Silent neonatal influenza A virus infection primes systemic antimicrobial immunity
per: Anna Sophie Heinemann, et al.
Publicat: (2023-01-01)

Mapping the interaction sites of human and avian influenza A viruses and complement factor H
per: Iman Rabeeah, et al.
Publicat: (2024-04-01)

Hepatitis C virus NS3/4A protease inhibits complement activation by cleaving complement component 4.
per: Seiichi Mawatari, et al.
Publicat: (2013-01-01)

Normal pathogen-specific immune responses mounted by CTLA-4-deficient T cells: a paradigm reconsidered.
per: Bachmann, M, et al.
Publicat: (2001)

Normal pathogen-specific immune responses mounted by CTLA-4-deficient T cells: a paradigm reconsidered.
per: Bachmann, M, et al.
Publicat: (2001)

Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells.
per: Bachmann, M, et al.
Publicat: (1999)

Migration and persistence of human influenza A viruses, Vietnam, 2001-2008.
per: Le, M, et al.
Publicat: (2013)

The first component of human complement
per: Sim, R
Publicat: (1976)

Promotion of the inflammatory response in mid colon of complement component 3 knockout mice
per: Yun Ju Choi, et al.
Publicat: (2022-02-01)

Structure of and influence of a tick complement inhibitor on human complement component 5.
per: Fredslund, F, et al.
Publicat: (2008)

Prime Graph over Cartesian Product over Rings and Its Complement
per: Farah Maulidya Fatimah, et al.
Publicat: (2023-07-01)

Complement C5 activation during influenza A infection in mice contributes to neutrophil recruitment and lung injury.
per: Cristiana C Garcia, et al.
Publicat: (2013-01-01)

The complement cascade in lung injury and disease
per: M. G. Detsika, et al.
Publicat: (2024-01-01)

Erratum: Structure of and influence of a tick complement inhibitor on human complement component 5.
per: Fredslund, F, et al.
Publicat: (2008)

Inhibition of c3 convertase activity by hepatitis C virus as an additional lesion in the regulation of complement components.
per: Hangeun Kim, et al.
Publicat: (2014-01-01)

Critical Role of HAX-1 in Promoting Avian Influenza Virus Replication in Lung Epithelial Cells
per: Xue Li, et al.
Publicat: (2018-01-01)

Benign Acute Myositis and Influenza Virus
per: J Gordon Millichap
Publicat: (1999-12-01)

Incomplete influenza A virus genomes occur frequently but are readily complemented during localized viral spread
per: Nathan T. Jacobs, et al.
Publicat: (2019-08-01)

The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts
per: Friščić, J, et al.
Publicat: (2021)

Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity
per: D. V. A. Khoa, et al.
Publicat: (2015-09-01)

Study of avian influenza virus circulation in uvs-nuur migration area in Republic of Tyva
per: M. S. Volkov, et al.
Publicat: (2018-04-01)

THE ISOLATION OF INFLUENZA A VIRUS FROM PLUMAGE OF WATERFOWL DURING AUTUMN MIGRATION
per: Marin A. Gulyaeva, et al.
Publicat: (2018-10-01)

Nano-modified viruses prime the tumor microenvironment and promote the photodynamic virotherapy in liver cancer
per: Da-Liang Ou, et al.
Publicat: (2024-01-01)

In the Crosshairs: RNA Viruses OR Complement?
per: Nisha Asok Kumar, et al.
Publicat: (2020-09-01)

Peripheral Leukocyte Migration in Ferrets in Response to Infection with Seasonal Influenza Virus.
per: Nedzad Music, et al.
Publicat: (2016-01-01)

Influenza a virus migration and persistence in North American wild birds.
per: Justin Bahl, et al.
Publicat: (2013-01-01)

Phylogenetic analysis reveals the global migration of seasonal influenza A viruses.
per: Martha I Nelson, et al.
Publicat: (2007-09-01)

Osteopontin is not required for the development of Th1 responses and viral immunity.
per: Abel, B, et al.
Publicat: (2005)

On the role of APC-activation for in vitro versus in vivo T cell priming.
per: Storni, T, et al.
Publicat: (2003)

Complement component 3 and complement factor H protein levels are altered in brain tissues from people with human immunodeficiency virus: A pilot study
per: Jerel Adam Fields, et al.
Publicat: (2022-08-01)