Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection.
The complement cascade defines an important link between the innate and the specific immune system. Here we show that mice deficient for the third component of complement (C3-/- mice) are highly susceptible to primary infection with influenza virus. C3-/- mice showed delayed viral clearance and incr...
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Journal article |
| Langue: | English |
| Publié: |
2002
|