Creation of an α-mannosynthase from a broad glycosidase scaffold.
α-Mannosides made easy: Mutation of a family-GH31 α-glucosidase that displays plasticity to alterations at the 2-OH position of donor substrates created an efficient α-mannoside-synthesizing biocatalyst. A simple fluoride donor reagent was used for the synthesis of a range of mono-α-mannosylated con...
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| Autori principali: |
Yamamoto, K,
Davis, B |
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| Natura: | Journal article
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| Lingua: | English |
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| Pubblicazione: |
2012
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