Creation of an α-mannosynthase from a broad glycosidase scaffold.
α-Mannosides made easy: Mutation of a family-GH31 α-glucosidase that displays plasticity to alterations at the 2-OH position of donor substrates created an efficient α-mannoside-synthesizing biocatalyst. A simple fluoride donor reagent was used for the synthesis of a range of mono-α-mannosylated con...
| Autori principali: | , |
|---|---|
| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
2012
|
| _version_ | 1826269994675077120 |
|---|---|
| author | Yamamoto, K Davis, B |
| author_facet | Yamamoto, K Davis, B |
| author_sort | Yamamoto, K |
| collection | OXFORD |
| description | α-Mannosides made easy: Mutation of a family-GH31 α-glucosidase that displays plasticity to alterations at the 2-OH position of donor substrates created an efficient α-mannoside-synthesizing biocatalyst. A simple fluoride donor reagent was used for the synthesis of a range of mono-α-mannosylated conjugates using the α-mannosynthase displaying low (unwanted) oligomerization activity. Copyright © 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim. |
| first_indexed | 2024-03-06T21:33:55Z |
| format | Journal article |
| id | oxford-uuid:459a8a18-01a3-4adb-bf45-d1ba1934bc49 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:33:55Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:459a8a18-01a3-4adb-bf45-d1ba1934bc492022-03-26T15:08:40ZCreation of an α-mannosynthase from a broad glycosidase scaffold.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:459a8a18-01a3-4adb-bf45-d1ba1934bc49EnglishSymplectic Elements at Oxford2012Yamamoto, KDavis, Bα-Mannosides made easy: Mutation of a family-GH31 α-glucosidase that displays plasticity to alterations at the 2-OH position of donor substrates created an efficient α-mannoside-synthesizing biocatalyst. A simple fluoride donor reagent was used for the synthesis of a range of mono-α-mannosylated conjugates using the α-mannosynthase displaying low (unwanted) oligomerization activity. Copyright © 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim. |
| spellingShingle | Yamamoto, K Davis, B Creation of an α-mannosynthase from a broad glycosidase scaffold. |
| title | Creation of an α-mannosynthase from a broad glycosidase scaffold. |
| title_full | Creation of an α-mannosynthase from a broad glycosidase scaffold. |
| title_fullStr | Creation of an α-mannosynthase from a broad glycosidase scaffold. |
| title_full_unstemmed | Creation of an α-mannosynthase from a broad glycosidase scaffold. |
| title_short | Creation of an α-mannosynthase from a broad glycosidase scaffold. |
| title_sort | creation of an α mannosynthase from a broad glycosidase scaffold |
| work_keys_str_mv | AT yamamotok creationofanamannosynthasefromabroadglycosidasescaffold AT davisb creationofanamannosynthasefromabroadglycosidasescaffold |