A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.

OBJECTIVE: To identify novel genes involved in osteoarthritis (OA), by means of a genome-wide association study. METHODS: We tested 500,510 single-nucleotide polymorphisms (SNPs) in 1,341 Dutch Caucasian OA cases and 3,496 Dutch Caucasian controls. SNPs associated with at least 2 OA phenotypes were...

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Main Authors: Kerkhof, H, Lories, R, Meulenbelt, I, Jonsdottir, I, Valdes, A, Arp, P, Ingvarsson, T, Jhamai, M, Jonsson, H, Stolk, L, Thorleifsson, G, Zhai, G, Zhang, F, Zhu, Y, van der Breggen, R, Carr, A, Doherty, M, Doherty, S, Felson, D, Gonzalez, A, Halldorsson, B, Hart, D, Hauksson, V, Hofman, A, Ioannidis, J
Format: Journal article
Language:English
Published: 2010

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