Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk.

Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk.

OBJECTIVE: Wolfram syndrome 1 (WFS1) single nucleotide polymorphisms (SNPs) are associated with risk of type 2 diabetes. In this study we aimed to refine this association and investigate the role of low-frequency WFS1 variants in type 2 diabetes risk. RESEARCH DESIGN AND METHODS: For fine-mapping, w...

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Hlavní autoři: Fawcett, K, Wheeler, E, Morris, A, Ricketts, S, Hallmans, G, Rolandsson, O, Daly, A, Wasson, J, Permutt, A, Hattersley, A, Glaser, B, Franks, P, McCarthy, M, Wareham, N, Sandhu, MS, Barroso, I
Médium: Journal article
Jazyk:English
Vydáno: 2010

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