Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.
Hypoxia is central to both ischaemic and neoplastic diseases. However, the non-coding transcriptional response to hypoxia is largely uncharacterized. We undertook integrated genomic analyses of both non-coding and coding transcripts using massively parallel sequencing and interfaced this data with p...
Main Authors: | Choudhry, H, Schödel, J, Oikonomopoulos, S, Camps, C, Grampp, S, Harris, A, Ratcliffe, P, Ragoussis, J, Mole, D |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2014
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