Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.
Hypoxia is central to both ischaemic and neoplastic diseases. However, the non-coding transcriptional response to hypoxia is largely uncharacterized. We undertook integrated genomic analyses of both non-coding and coding transcripts using massively parallel sequencing and interfaced this data with p...
Κύριοι συγγραφείς: | Choudhry, H, Schödel, J, Oikonomopoulos, S, Camps, C, Grampp, S, Harris, A, Ratcliffe, P, Ragoussis, J, Mole, D |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2014
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Παρόμοια τεκμήρια
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Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2
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Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.
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Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.
ανά: Mole, D, κ.ά.
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