Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.

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Hypoxia is central to both ischaemic and neoplastic diseases. However, the non-coding transcriptional response to hypoxia is largely uncharacterized. We undertook integrated genomic analyses of both non-coding and coding transcripts using massively parallel sequencing and interfaced this data with p...

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Detalles Bibliográficos
Main Authors: Choudhry, H, Schödel, J, Oikonomopoulos, S, Camps, C, Grampp, S, Harris, A, Ratcliffe, P, Ragoussis, J, Mole, D
Formato: Journal article
Idioma:English
Publicado: 2014

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