Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.
Hypoxia is central to both ischaemic and neoplastic diseases. However, the non-coding transcriptional response to hypoxia is largely uncharacterized. We undertook integrated genomic analyses of both non-coding and coding transcripts using massively parallel sequencing and interfaced this data with p...
Hauptverfasser: | , , , , , , , , |
---|---|
Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2014
|