Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET.
Hypoxia in solid tumours is associated with the promotion of various metabolic mechanisms and induces resistance to radio- and chemotherapy. Non-invasive positron emission tomography (PET) or single photon emission computed tomography by use of selective biomarkers has emerged as valuable tools for...
Hlavní autoři: | Bejot, R, Kersemans, V, Kelly, C, Carroll, L, King, R, Gouverneur, V, Elizarov, A, Ball, C, Zhang, J, Miraghaie, R, Kolb, H, Smart, S, Hill, S |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2010
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