Association of the GNAS locus with severe malaria.

Association of the GNAS locus with severe malaria.

Functional studies have demonstrated an interaction between the stimulatory G protein alpha subunit (G-alpha-s) and the malaria parasite at a cellular level. Obstruction of signal transduction via the erythrocyte G-alpha-s subunit reduced invasion by Plasmodium falciparum parasites. We sought to det...

Descripción completa

Detalles Bibliográficos
Autores principales: Auburn, S, Diakite, M, Fry, A, Ghansah, A, Campino, S, Richardson, A, Jallow, M, Sisay-Joof, F, Pinder, M, Griffiths, M, Peshu, N, Williams, T, Marsh, K, Molyneux, M, Taylor, T, Koram, K, Oduro, A, Rogers, W, Rockett, K, Haldar, K, Kwiatkowski, D
Formato: Journal article
Lenguaje:English
Publicado: 2008

Ejemplares similares