Differential properties of Janus kinase inhibitors in the treatment of immune-mediated inflammatory diseases
Janus kinases (JAKs) are a family of cytosolic tyrosine kinases that regulate cytokine signal transduction, including cytokines involved in a range of inflammatory diseases, such as rheumatoid arthritis, psoriasis, atopic dermatitis, and inflammatory bowel disease. Several small-molecule JAK inhibit...
Main Authors: | Taylor, PC, Choy, E, Baraliakos, X, Szekanecz, Z, Xavier, RM, Isaacs, JD, Strengholt, S, Parmentier, JM, Lippe, R, Tanaka, Y |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2023
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