Differential properties of Janus kinase inhibitors in the treatment of immune-mediated inflammatory diseases

Janus kinases (JAKs) are a family of cytosolic tyrosine kinases that regulate cytokine signal transduction, including cytokines involved in a range of inflammatory diseases, such as rheumatoid arthritis, psoriasis, atopic dermatitis, and inflammatory bowel disease. Several small-molecule JAK inhibit...

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Những tác giả chính: Taylor, PC, Choy, E, Baraliakos, X, Szekanecz, Z, Xavier, RM, Isaacs, JD, Strengholt, S, Parmentier, JM, Lippe, R, Tanaka, Y
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Oxford University Press 2023