Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival

<p><strong>Background:</strong> Glioblastoma is the most common and aggressive primary brain tumor with extremely poor prognosis, highlighting an urgent need for developing novel treatment options. Identifying epigenetic vulnerabilities of cancer cells can provide excellen...

書目詳細資料
Main Authors:	Ozyerli-Goknar, E, Kala, EY, Aksu, AC, Bulut, I, Cingöz, A, Nizamuddin, S, Biniossek, M, Seker-Polat, F, Morova, T, Aztekin, C, Kung, SHY, Syed, H, Tuncbag, N, Gönen, M, Philpott, M, Cribbs, AP, Acilan, C, Lack, NA, Onder, TT, Timmers, HTM, Bagci-Onder, T
格式:	Journal article
語言:	English
出版:	BioMed Central 2023

相似書籍

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival
由: Ezgi Ozyerli-Goknar, et al.
出版: (2023-11-01)

EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities
由: Yedier-Bayram, O, et al.
出版: (2022)

The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma
由: Ozyerli-Goknar, E, et al.
出版: (2019)

Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer
由: Saraç, H, et al.
出版: (2019)

Homeotic shift at the dawn of the turtle evolution
由: Tomasz Szczygielski
出版: (2017-01-01)

EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities
由: Ozlem Yedier-Bayram, et al.
出版: (2022-08-01)

Floral Homeotic Factors: A Question of Specificity
由: Kevin Goslin, et al.
出版: (2023-03-01)

Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer
由: Gokbayrak, B, et al.
出版: (2025)

Multi-omics analyses of MEN1 missense mutations identify disruption of menin–MLL and menin–JunD interactions as critical requirements for molecular pathogenicity
由: Koen M. A. Dreijerink, et al.
出版: (2022-08-01)

Homeotic transformations and number changes in the vertebral column of Triturus newts
由: Maja Slijepčević, et al.
出版: (2015-11-01)

Homeotic compartment curvature and tension control spatiotemporal folding dynamics
由: Aurélien Villedieu, et al.
出版: (2023-02-01)

Functional evolution of cis-regulatory modules at a homeotic gene in Drosophila.
由: Margaret C W Ho, et al.
出版: (2009-11-01)

Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming
由: Ebrahimi, A, et al.
出版: (2019)

Expression Pattern of a Homeotic Gene, HOXA5, in Normal Breast and in Breast Tumors
由: Gregory S. Henderson, et al.
出版: (2006-01-01)

Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton.
由: Esther Tijchon, et al.
出版: (2015-01-01)

Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome
由: Tian Yu, et al.
出版: (2013-12-01)

Arabidopsis TCP4 transcription factor inhibits high temperature-induced homeotic conversion of ovules
由: Jingqiu Lan, et al.
出版: (2023-09-01)

Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids
由: Jitu Wilson George, et al.
出版: (2019-12-01)

Phenotypic characterization and genetic variability of Muthu Mullai mutants ofJasminum auriculatum for induction of homeotic mutants
由: S P MIRUNALINI, et al.
出版: (2024-07-01)

Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
由: Buse Cevatemre, et al.
出版: (2024-02-01)

Image of the Absent
由: Ayellet Ben Ner
出版: (2015-10-01)

Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer
由: Bengul Gokbayrak, et al.
出版: (2025-02-01)

HOX epimutations driven by maternal SMCHD1/LRIF1 haploinsufficiency trigger homeotic transformations in genetically wildtype offspring
由: Shifeng Xue, et al.
出版: (2022-06-01)

Interpeler l’absent.
由: Marie-Laure Florea
出版: (2010-10-01)

Team 10 Absent
由: Ana Esteban Maluenda
出版: (2019-12-01)

Le peuple absent
由: Nejma Kermele
出版: (2017-12-01)

The Additional sex combs gene of Drosophila is required for activation and repression of homeotic loci, and interacts specifically with Polycomb and super sex combs.
由: Milne, T, et al.
出版: (1999)

Different Ectopic Hoxa2 Expression Levels in Mouse Cranial Neural Crest Cells Result in Distinct Craniofacial Anomalies and Homeotic Phenotypes
由: Taro Kitazawa, et al.
出版: (2022-01-01)

Ectopic expression of CsMADS24, an AGAMOUS ortholog from cucumber, causes homeotic conversion of sepals into carpels in transgenic arabidopsis plants
由: Zhou Yong, et al.
出版: (2019-01-01)

The not-so-absent-minded driver
由: Board, O
出版: (2003)

Kant and the Modernity of the Absent Public
由: Jarzombek, Mark
出版: (2019)

The Not-So-Absent-Minded Driver.
由: Board, O
出版: (2003)

The absent pulmonary valve syndrome
由: A Bilgiç, et al.
出版: (1982-04-01)

Retour de l’absent
由: Claire Demesmay, et al.
出版: (2018-11-01)

Absent Labial Frenulum in Holoprosencephaly
由: J Gordon Millichap
出版: (1998-08-01)

THE ABSENT GEOPOLITICS OF PURE CAPITALISM
由: Radhika Desai
出版: (2010-09-01)

Listening by ‘Staying With’ the Absent Child
由: Alex Orrmalm, et al.
出版: (2022-10-01)

On finding minimal absent words
由: Garcia Sara P, et al.
出版: (2009-05-01)

Poland syndrome with absent ribs
由: Rupam Kumar Ta, et al.
出版: (2014-01-01)

Endlessly Signifying What Is Absent
由: Jean Frémon
出版: (1987-08-01)