Nonreciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription.
Chromosomal translocations and other abnormalities are central to the initiation of cancer in all cell types. Understanding the mechanism is therefore important to evaluate the evolution of cancer from the cancer initiating events to overt disease. Recent work has concentrated on model systems to de...
Κύριοι συγγραφείς: | Ali, H, Daser, A, Dear, P, Wood, H, Rabbitts, P, Rabbitts, T |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2013
|
Παρόμοια τεκμήρια
-
Nonreciprocal chromosomal translocations in renal cancer involve multiple DSBs and NHEJ associated with breakpoint inversion but not necessarily with transcription
ανά: Ali, H, κ.ά.
Έκδοση: (2013) -
Chromosomal translocation master genes, mouse models and experimental therapeutics.
ανά: Rabbitts, T
Έκδοση: (2001) -
Chromosomal translocation products engender new intracellular therapeutic technologies.
ανά: Rabbitts, T, κ.ά.
Έκδοση: (2003) -
The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumour tropism.
ανά: Collins, E, κ.ά.
Έκδοση: (2002) -
The role of LMO2 in development and in T cell leukemia after chromosomal translocation or retroviral insertion.
ανά: Nam, C, κ.ά.
Έκδοση: (2006)