Blocking IL-1α but not IL-1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice.

IL-1α and IL-1β are potent inflammatory cytokines and important mediators of immune responses to intracellular pathogens such as Mycobacterium tuberculosis (Mtb). Here, we investigated the role of IL-1α and IL-1β during chronic Mtb infection and spontaneous reactivation in mice. For long-term neutra...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Guler, R, Parihar, S, Spohn, G, Johansen, P, Brombacher, F, Bachmann, M
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2011