Aldehyde dehydrogenase-2 inhibition blocks remote preconditioning in experimental and human models.

Aldehyde dehydrogenase-2 inhibition blocks remote preconditioning in experimental and human models.

Εμφάνιση άλλων εκδόσεων (1)

Mitochondrial aldehyde dehydrogenase-2 (ALDH-2) is involved in preconditioning pathways, but its role in remote ischaemic preconditioning (rIPC) is unknown. We investigated its role in animal and human models of rIPC. (i) In a rabbit model of myocardial infarction, rIPC alone reduced infarct size [6...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Contractor, H, Støttrup, N, Cunnington, C, Manlhiot, C, Diesch, J, Ormerod, J, Jensen, R, Bøtker, H, Redington, A, Schmidt, MR, Ashrafian, H, Kharbanda, R
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2013

Παρόμοια τεκμήρια

Aldehyde dehydrogenase-2 inhibition blocks remote preconditioning in experimental and human models
ανά: Contractor, H, κ.ά.
Έκδοση: (2013)

Aldehyde dehydrogenase-2 is necessary for remote preconditioning
ανά: Contractor, H, κ.ά.
Έκδοση: (2011)

Remote ischemic preconditioning impairs ventricular function and increases infarct size after prolonged ischemia in the isolated neonatal rabbit heart
ανά: Schmidt, MR, κ.ά.
Έκδοση: (2014)

Remote ischemic preconditioning impairs ventricular function and increases infarct size after prolonged ischemia in the isolated neonatal rabbit heart.
ανά: Schmidt, MR, κ.ά.
Έκδοση: (2014)

Remote ischemic preconditioning with - but not without - metabolic support protects the neonatal porcine heart against ischemia-reperfusion injury
ανά: Schmidt, MR, κ.ά.
Έκδοση: (2014)

Remote ischemic preconditioning with--but not without--metabolic support protects the neonatal porcine heart against ischemia-reperfusion injury.
ανά: Schmidt, MR, κ.ά.
Έκδοση: (2014)

Immature hearts respond metabolically different to remote ischemic preconditioning than mature hearts: A tracer
ανά: Stottrup, N, κ.ά.
Έκδοση: (2009)

Inorganic Nitrite Induces Second-Window Preconditioning in Healthy Volunteers
ανά: Ormerod, J, κ.ά.
Έκδοση: (2011)

ADENOSINE RECEPTOR INHIBITION ABOLISHES REMOTE ISCHAEMIC PRECONDITIONING IN HUMANS
ανά: Contractor, H, κ.ά.
Έκδοση: (2009)

LOCAL ISCHEMIC PRECONDITIONING PROTECTS AGAINST ENDOTHELIAL DYSFUNCTION IN A NOVEL EX-VIVO MODEL OF HUMAN VASCULAR ISCHEMIA-REPERFUSION INJURY
ανά: Juul-Dam, K, κ.ά.
Έκδοση: (2009)

Pretreatment with the nitric oxide donor SNAP or nerve transection blocks humoral preconditioning by remote limb ischemia or intra-arterial adenosine.
ανά: Steensrud, T, κ.ά.
Έκδοση: (2010)

Increased Beta-Catenin Pathway Expression by a Remote Ischaemic Preconditioning Stimulus: First Evidence in Humans
ανά: Contractor, H, κ.ά.
Έκδοση: (2009)

BETA-CATENIN PATHWAY EXPRESSION IN HUMAN MYOCARDIUM IS INCREASED BY A REMOTE ISCHAEMIC PRECONDITIONING STIMULUS
ανά: Contractor, H, κ.ά.
Έκδοση: (2009)

Remote preconditioning reduces ischemic injury in the explanted heart by a KATP channel-dependent mechanism.
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PERIPHERAL ARTERIAL ADENOSINE INFUSION DURING CORONARY ISCHAEMIA REDUCES MYOCARDIAL INFARCTION
ανά: Contractor, H, κ.ά.
Έκδοση: (2009)

Remote Ischemic Preconditioning with - but not Without - Metabolic Support Protects Against Ischemia-Reperfusion Injury in the Newborn Piglet In-vivo
ανά: Schmidt, MR, κ.ά.
Έκδοση: (2012)

Local preconditioning protects against endothelial ischemia-reperfusion injury in human blood vessel in-vitro
ανά: Juul-Dam, K, κ.ά.
Έκδοση: (2009)

REMOTE ISCHEMIC PRECONDITIONING IS NOT MEDIATED BY ENDOGENOUS BRADYKININ IN HUMANS
ανά: Pedersen, C, κ.ά.
Έκδοση: (2011)

Translation of remote ischaemic preconditioning into clinical practice.
ανά: Kharbanda, R, κ.ά.
Έκδοση: (2009)

Potentiating mitochondrial aldehyde dehydrogenase 2 to treat post-infarction heart failure.
ανά: Yavari, A, κ.ά.
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Remote ischemic preconditioning prevents systemic platelet activation associated with ischemia-reperfusion injury in humans.
ανά: Pedersen, C, κ.ά.
Έκδοση: (2011)

Remote ischemic preconditioning prevents systemic platelet activation associated with ischemia-reperfusion injury in humans
ανά: Pedersen, C, κ.ά.
Έκδοση: (2011)

Bradykinin does not mediate remote ischaemic preconditioning or ischaemia-reperfusion injury in vivo in man
ανά: Pedersen, C, κ.ά.
Έκδοση: (2011)

Bradykinin does not mediate remote ischaemic preconditioning or ischaemia-reperfusion injury in vivo in man.
ανά: Pedersen, C, κ.ά.
Έκδοση: (2011)

Second window and chronic remote ischemic conditioning prevent endothelial injury by ischemia-reperfusion in humans
ανά: Pryds, K, κ.ά.
Έκδοση: (2012)

ALDH2 GENOTYPE INFLUENCES THE PROTECTION OF ENDOTHELIUM AGAINST ISCHEMIC INJURY BY SYSTEMIC NITRITE
ανά: Ormerod, J, κ.ά.
Έκδοση: (2011)

Preserved flow-mediated dilation in adults with cyanotic congenital heart disease.
ανά: Pedersen, C, κ.ά.
Έκδοση: (2009)

Preserved Flow-Mediated Dilation in Adults with Cyanotic Congenital Heart Disease
ανά: Pedersen, C, κ.ά.
Έκδοση: (2009)

Preserved flow-mediated dilation in adults with cyanotic congenital heart disease
ανά: Pedersen, C, κ.ά.
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Transient limb ischemia induces remote ischemic preconditioning in vivo.
ανά: Kharbanda, R, κ.ά.
Έκδοση: (2002)

Intermittent limb ischemia during coronary ischaemia reduces myocardial infarction through a K-ATP dependent mechanism: Demonstration of remote ischemic preconditioning
ανά: Schmidt, M, κ.ά.
Έκδοση: (2006)

Remote ischemic preconditioning modifies coronary flow and resistance via Katp-dependent mechanism
ανά: Shimizu, M, κ.ά.
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SAXS fingerprints of aldehyde dehydrogenase oligomers
ανά: John J. Tanner
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Remote Ischemic Perconditioning Improves Long-Term Clinical Outcome in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction
ανά: Sloth, A, κ.ά.
Έκδοση: (2012)

Remote Ischemic Preconditioning Modifies Cardiac Micro RNA Expression In Vivo: First Observations in a Mouse Model
ανά: Li, J, κ.ά.
Έκδοση: (2009)

Improved long-term clinical outcomes in patients with ST-elevation myocardial infarction undergoing remote ischaemic conditioning as an adjunct to primary percutaneous coronary intervention.
ανά: Sloth, A, κ.ά.
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A randomized pilot trial of remote ischemic preconditioning in heart failure with reduced ejection fraction.
ανά: Michael A McDonald, κ.ά.
Έκδοση: (2014-01-01)

MicroRNA-144 is a circulating effector of remote ischemic preconditioning.
ανά: Li, J, κ.ά.
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Update on the aldehyde dehydrogenase gene (<it>ALDH</it>) superfamily
ανά: Jackson Brian, κ.ά.
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Transient limb ischemia induces remote ischemic preconditioning in vivo - Response
ανά: Kharbanda, R, κ.ά.
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