Aldehyde dehydrogenase-2 inhibition blocks remote preconditioning in experimental and human models.

Aldehyde dehydrogenase-2 inhibition blocks remote preconditioning in experimental and human models.

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Mitochondrial aldehyde dehydrogenase-2 (ALDH-2) is involved in preconditioning pathways, but its role in remote ischaemic preconditioning (rIPC) is unknown. We investigated its role in animal and human models of rIPC. (i) In a rabbit model of myocardial infarction, rIPC alone reduced infarct size [6...

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Autori principali:	Contractor, H, Støttrup, N, Cunnington, C, Manlhiot, C, Diesch, J, Ormerod, J, Jensen, R, Bøtker, H, Redington, A, Schmidt, MR, Ashrafian, H, Kharbanda, R
Natura:	Journal article
Lingua:	English
Pubblicazione:	2013

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