The LFA-1 I-domain: A transient low affinity binding module for ICAM-1

The LFA-1 I-domain: A transient low affinity binding module for ICAM-1

Lymphocyte function associated antigen 1 (LFA-1) is a heterodimer, composed of an α L-chain and a β 2-chain. The I-domain is inserted in the ctL-chain and contains a binding site for ICAM-1. To study the adhesive interaction between the I-domain and IC...

Full description

Bibliographic Details
Main Authors:	Knorr, R, Dustin, M
Format:	Journal article
Language:	English
Published:	1996

Similar Items

The lymphocyte function-associated antigen 1 I domain is a transient binding module for intercellular adhesion molecule (ICAM)-1 and ICAM-3 in hydrodynamic flow.
by: Knorr, R, et al.
Published: (1997)

The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus.
by: Staunton, D, et al.
Published: (1990)

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1.
by: Staunton, D, et al.
Published: (1989)

Role of LFA-1 and ICAM-1 in Cancer
by: Manuel Reina, et al.
Published: (2017-11-01)

Structure and regulation of the leukocyte adhesion receptor LFA-1 and its counterreceptors, ICAM-1 and ICAM-2.
by: Dustin, M, et al.
Published: (1989)

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.
by: Rothlein, R, et al.
Published: (1986)

Low affinity of cell surface lymphocyte function-associated antigen-1 (LFA-1) generates selectivity for cell-cell interactions.
by: Ganpule, G, et al.
Published: (1997)

Regulation of locomotion and cell-cell contact area by the LFA-1 and ICAM-1 adhesion receptors.
by: Dustin, M, et al.
Published: (1992)

ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells.
by: Makgoba, M, et al.
Published: (1988)

Motility and ultrastructure of large granular lymphocytes on lipid bilayers reconstituted with adhesion receptors LFA-1, ICAM-1, and two isoforms of LFA-3.
by: Carpén, O, et al.
Published: (1991)

The binding site on ICAM-1 for Plasmodium falciparum-infected erythrocytes overlaps, but is distinct from, the LFA-1-binding site.
by: Berendt, A, et al.
Published: (1992)

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J. Immunol. 1986. 137: 1270-1274.
by: Rothlein, R, et al.
Published: (2011)

A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye
by: Pang-Yu Hsueh, et al.
Published: (2020-04-01)

LFA-1/ICAM-1 interaction lowers the threshold of B cell activation by facilitating B cell adhesion and synapse formation.
by: Carrasco, Y, et al.
Published: (2004)

ICAM-1 and ICAM-2 Are Differentially Expressed and Up-Regulated on Inflamed Pulmonary Epithelium, but Neither ICAM-2 nor LFA-1: ICAM-1 Are Required for Neutrophil Migration Into the Airways In Vivo
by: Deborah L. W. Chong, et al.
Published: (2021-08-01)

Examining the Effect of Kindlin-3 Binding Site Mutation on LFA-1-ICAM-1 Bonds by Force Measuring Optical Tweezers
by: Craig McDonald, et al.
Published: (2022-01-01)

Functional evidence that intercellular adhesion molecule-1 (ICAM-1) is a ligand for LFA-1-dependent adhesion in T cell-mediated cytotoxicity.
by: Makgoba, M, et al.
Published: (1988)

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1.
by: Dustin, M, et al.
Published: (1989)

Endocan (ESM-1) levels in gingival crevicular fluid correlate with ICAM-1 and LFA-1 in periodontitis
by: Mahmure Ayşe Tayman, et al.
Published: (2020-11-01)

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.
by: Dustin, M, et al.
Published: (1988)

Small GTPases and LFA-1 reciprocally modulate adhesion and signaling.
by: Mor, A, et al.
Published: (2007)

Making a little affinity go a long way: a topological view of LFA-1 regulation.
by: Dustin, M
Published: (1998)

LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model.
by: Nannan Gao, et al.
Published: (2022-10-01)

Galectin-8 binds to LFA-1, blocks its interaction with ICAM-1 and is counteracted by anti-Gal-8 autoantibodies isolated from lupus patients
by: Lucas Vicuña, et al.
Published: (2013-01-01)

The Regulation of ICAM-1 and LFA-1 Interaction by Autacoids and Statins: a Novel Strategy for Controlling Inflammation and Immune Responses
by: Masahiro Nishibori, et al.
Published: (2003-01-01)

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4
by: Juan Manel, et al.
Published: (2008-03-01)

Distinct Roles of LFA-1 and ICAM-1 on ILC2s Control Lung Infiltration, Effector Functions, and Development of Airway Hyperreactivity
by: Benjamin P. Hurrell, et al.
Published: (2020-10-01)

ICAM-1-LFA-1 Dependent CD8+ T-Lymphocyte Aggregation in Tumor Tissue Prevents Recirculation to Draining Lymph Nodes
by: Alba Yanguas, et al.
Published: (2018-09-01)

The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system.
by: Springer, T, et al.
Published: (1987)

T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions
by: Alvaro Teijeira, et al.
Published: (2017-01-01)

Utilization of I-domain of LFA-1 to target drug and marker molecules to Leukocytes.
by: Manikwar, Prakash, et al.
Published: (2011)

Utilization of I-domain of LFA-1 to Target Drug and Marker Molecules to Leukocytes
by: Prakash Manikwar, Bimo A. Tejo, Heather Shinogle, David S. Moore, Tahl Zimmerman, Francisco Blanco, Teruna J. Siahaan
Published: (2011-01-01)

Two-way signalling through the LFA-1 lymphocyte adhesion receptor.
by: Dustin, M
Published: (1990)

Percentage of LFA-1+ and ICAM-1+ peripheral blood mononuclear cells in children and adolescents with type 1 diabetes does not distinguish patients with vascular complications.
by: Anna Stasiak-Barmuta, et al.
Published: (2009-12-01)

The interaction of LFA-1 on mononuclear cells and ICAM-1 on tubular epithelial cells accelerates TGF-β1-induced renal epithelial-mesenchymal transition.
by: Yoshiyuki Morishita, et al.
Published: (2011-01-01)

LFA-1/ICAM-1 Adhesion Pathway Mediates the Homeostatic Migration of Lymphocytes from Peripheral Tissues into Lymph Nodes through Lymphatic Vessels
by: Jia Guo, et al.
Published: (2023-07-01)

FRET based quantification and screening technology platform for the interactions of leukocyte function-associated antigen-1 (LFA-1) with intercellular adhesion molecule-1 (ICAM-1).
by: Sandeep Chakraborty, et al.
Published: (2014-01-01)

On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules.
by: Johnston, S, et al.
Published: (1990)

LFA-1/ICAM-1 ligation in human T cells promotes Th1 polarization through a GSK3β signaling–dependent notch pathway
by: Ong, Seow Theng, et al.
Published: (2018)

Characterization of intercellular adhesion molecule-1 ectodomain (sICAM-1) as an inhibitor of lymphocyte function-associated molecule-1 interaction with ICAM-1.
by: Meyer, D, et al.
Published: (1995)