Screening for hypercholesterolaemia versus case finding for familial hypercholesterolaemia: a systematic review and cost-effectiveness analysis.

BACKGROUND: In the majority of people with familial hypercholesterolaemia (FH) the disorder is caused by a mutation of the low-density lipoprotein receptor gene that impairs its proper function, resulting in very high levels of plasma cholesterol. Such levels result in early and severe atheroscleros...

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Autors principals: Marks, D, Wonderling, D, Thorogood, M, Lambert, H, Humphries, SE, Neil, H
Format: Journal article
Idioma:English
Publicat: 2000