Mechanism of ATP-sensitive K channel inhibition by sulfhydryl modification.

Mechanism of ATP-sensitive K channel inhibition by sulfhydryl modification.

ATP-sensitive potassium (KATP) channels are reversibly inhibited by intracellular ATP. Agents that interact with sulfhydryl moieties produce an irreversible inhibition of KATP channel activity when applied to the intracellular membrane surface. ATP appears to protect against this effect, suggesting...

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Bibliographic Details
Main Authors:	Trapp, S, Tucker, S, Ashcroft, F
Format:	Journal article
Language:	English
Published:	1998

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