Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2.
We have identified an HLA-A2-restricted CD8(+) T-cell epitope, FLYALALLL, in the Epstein-Barr virus (EBV) latent membrane protein 2 (LMP2), an important target antigen in the context of EBV-associated malignancies. This epitope is TAP independent, like other hydrophobic LMP2-derived epitopes, but un...
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Bibliografiske detaljer
| Main Authors: |
Lautscham, G,
Haigh, T,
Mayrhofer, S,
Taylor, G,
Croom-Carter, D,
Leese, A,
Gadola, S,
Cerundolo, V,
Rickinson, A,
Blake, N |
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| Format: | Journal article
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| Sprog: | English |
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| Udgivet: |
2003
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