Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2.

We have identified an HLA-A2-restricted CD8(+) T-cell epitope, FLYALALLL, in the Epstein-Barr virus (EBV) latent membrane protein 2 (LMP2), an important target antigen in the context of EBV-associated malignancies. This epitope is TAP independent, like other hydrophobic LMP2-derived epitopes, but un...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Lautscham, G, Haigh, T, Mayrhofer, S, Taylor, G, Croom-Carter, D, Leese, A, Gadola, S, Cerundolo, V, Rickinson, A, Blake, N
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2003