A transcriptomics-based investigation of the landscape and mechanisms of self-antigen splicing in thymic epithelial cells

<p>Thymic epithelial cells (TEC) are remarkable for their ability to promiscuously express virtually the entire protein-coding gene repertoire to generate a molecular library of self-antigens for T cell education and selection. This process is essential for the establishment of central T cell...

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Bibliographic Details
Main Author: Jansen, K
Other Authors: Sansom, S
Format: Thesis
Published: 2019

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